diff --git a/NEWS b/NEWS
index 68d5ff5ea9c..fd9a08f0f40 100644
--- a/NEWS
+++ b/NEWS
@@ -8,6 +8,8 @@ PHP                                                                        NEWS
 - Core:
   . Fixed bug OSS-Fuzz #371445205 (Heap-use-after-free in attr_free).
     (nielsdos)
+  . Fixed bug GH-16168 (php 8.1 and earlier crash immediately when compiled
+    with Xcode 16 clang on macOS 15). (nielsdos)
 
 - Curl:
   . Fixed bug GH-16302 (CurlMultiHandle holds a reference to CurlHandle if
diff --git a/Zend/zend_string.c b/Zend/zend_string.c
index 7a00171d2c8..dfe059359aa 100644
--- a/Zend/zend_string.c
+++ b/Zend/zend_string.c
@@ -402,32 +402,32 @@ ZEND_API bool ZEND_FASTCALL I_REPLACE_SONAME_FNNAME_ZU(NONE,zend_string_equal_va
 ZEND_API zend_never_inline NOIPA bool ZEND_FASTCALL zend_string_equal_val(const zend_string *s1, const zend_string *s2)
 {
 	const char *ptr = ZSTR_VAL(s1);
-	size_t delta = (const char*)s2 - (const char*)s1;
+	uintptr_t delta = (uintptr_t) s2 - (uintptr_t) s1;
 	size_t len = ZSTR_LEN(s1);
 	zend_ulong ret;
 
 	__asm__ (
-		".LL0%=:\n\t"
+		"0:\n\t"
 		"movl (%2,%3), %0\n\t"
 		"xorl (%2), %0\n\t"
-		"jne .LL1%=\n\t"
+		"jne 1f\n\t"
 		"addl $0x4, %2\n\t"
 		"subl $0x4, %1\n\t"
-		"ja .LL0%=\n\t"
+		"ja 0b\n\t"
 		"movl $0x1, %0\n\t"
-		"jmp .LL3%=\n\t"
-		".LL1%=:\n\t"
+		"jmp 3f\n\t"
+		"1:\n\t"
 		"cmpl $0x4,%1\n\t"
-		"jb .LL2%=\n\t"
+		"jb 2f\n\t"
 		"xorl %0, %0\n\t"
-		"jmp .LL3%=\n\t"
-		".LL2%=:\n\t"
+		"jmp 3f\n\t"
+		"2:\n\t"
 		"negl %1\n\t"
 		"lea 0x20(,%1,8), %1\n\t"
 		"shll %b1, %0\n\t"
 		"sete %b0\n\t"
 		"movzbl %b0, %0\n\t"
-		".LL3%=:\n"
+		"3:\n"
 		: "=&a"(ret),
 		  "+c"(len),
 		  "+r"(ptr)
@@ -440,32 +440,32 @@ ZEND_API zend_never_inline NOIPA bool ZEND_FASTCALL zend_string_equal_val(const
 ZEND_API zend_never_inline NOIPA bool ZEND_FASTCALL zend_string_equal_val(const zend_string *s1, const zend_string *s2)
 {
 	const char *ptr = ZSTR_VAL(s1);
-	size_t delta = (const char*)s2 - (const char*)s1;
+	uintptr_t delta = (uintptr_t) s2 - (uintptr_t) s1;
 	size_t len = ZSTR_LEN(s1);
 	zend_ulong ret;
 
 	__asm__ (
-		".LL0%=:\n\t"
+		"0:\n\t"
 		"movq (%2,%3), %0\n\t"
 		"xorq (%2), %0\n\t"
-		"jne .LL1%=\n\t"
+		"jne 1f\n\t"
 		"addq $0x8, %2\n\t"
 		"subq $0x8, %1\n\t"
-		"ja .LL0%=\n\t"
+		"ja 0b\n\t"
 		"movq $0x1, %0\n\t"
-		"jmp .LL3%=\n\t"
-		".LL1%=:\n\t"
+		"jmp 3f\n\t"
+		"1:\n\t"
 		"cmpq $0x8,%1\n\t"
-		"jb .LL2%=\n\t"
+		"jb 2f\n\t"
 		"xorq %0, %0\n\t"
-		"jmp .LL3%=\n\t"
-		".LL2%=:\n\t"
+		"jmp 3f\n\t"
+		"2:\n\t"
 		"negq %1\n\t"
 		"lea 0x40(,%1,8), %1\n\t"
 		"shlq %b1, %0\n\t"
 		"sete %b0\n\t"
 		"movzbq %b0, %0\n\t"
-		".LL3%=:\n"
+		"3:\n"
 		: "=&a"(ret),
 		  "+c"(len),
 		  "+r"(ptr)